| Cape Girardeau to Dallas (Texas) | 513.13 mi (825.81 km) |
| Cape Girardeau to Dalton (Georgia) | 310.65 mi (499.94 km) |
| Cape Girardeau to Daly City (California) | 1,794.75 mi (2,888.38 km) |
| Cape Girardeau to Damascus (Maryland) | 683.44 mi (1,099.90 km) |
| Cape Girardeau to Damascus (Oregon) | 1,780.51 mi (2,865.46 km) |
| Cape Girardeau to Dana Point (California) | 1,600.77 mi (2,576.19 km) |
| Cape Girardeau to Danbury (Connecticut) | 903.20 mi (1,453.56 km) |
| Cape Girardeau to Dania Beach (Florida) | 952.50 mi (1,532.90 km) |
| Cape Girardeau to Danville (California) | 1,766.47 mi (2,842.86 km) |
| Cape Girardeau to Danville (Illinois) | 222.05 mi (357.35 km) |
| Cape Girardeau to Danville (Indiana) | 236.42 mi (380.48 km) |
| Cape Girardeau to Danville (Kentucky) | 263.18 mi (423.54 km) |
| Cape Girardeau to Danville (Virginia) | 562.50 mi (905.25 km) |
| Cape Girardeau to Daphne (Alabama) | 471.74 mi (759.19 km) |
| Cape Girardeau to Darby (Pennsylvania) | 791.76 mi (1,274.22 km) |
