| Cape Girardeau to Frankfort (Illinois) | 302.98 mi (487.60 km) |
| Cape Girardeau to Frankfort (Indiana) | 262.42 mi (422.33 km) |
| Cape Girardeau to Frankfort (Kentucky) | 263.61 mi (424.24 km) |
| Cape Girardeau to Franklin (Indiana) | 242.44 mi (390.16 km) |
| Cape Girardeau to Franklin (Ohio) | 324.27 mi (521.86 km) |
| Cape Girardeau to Franklin (Tennessee) | 178.29 mi (286.93 km) |
| Cape Girardeau to Franklin (Wisconsin) | 393.75 mi (633.68 km) |
| Cape Girardeau to Franklin Farm (Virginia) | 669.88 mi (1,078.07 km) |
| Cape Girardeau to Franklin Lakes (New Jersey) | 859.86 mi (1,383.81 km) |
| Cape Girardeau to Franklin Park (Illinois) | 331.83 mi (534.02 km) |
| Cape Girardeau to Franklin Park (New Jersey) | 835.05 mi (1,343.89 km) |
| Cape Girardeau to Franklin Park (Pennsylvania) | 556.12 mi (894.99 km) |
| Cape Girardeau to Franklin Square (New York) | 882.90 mi (1,420.90 km) |
| Cape Girardeau to Fraser (Michigan) | 502.82 mi (809.21 km) |
| Cape Girardeau to Frederick (Colorado) | 851.85 mi (1,370.92 km) |
