| Carlisle to Spello | 1,080.66 mi (1,739.15 km) |
| Carlisle to Spilamberto | 945.82 mi (1,522.16 km) |
| Carlisle to Spilimbergo | 918.36 mi (1,477.96 km) |
| Carlisle to Spinea | 928.01 mi (1,493.48 km) |
| Carlisle to Spoleto | 1,094.23 mi (1,760.99 km) |
| Carlisle to Spoltore | 1,153.98 mi (1,857.15 km) |
| Carlisle to Spresiano | 915.61 mi (1,473.53 km) |
| Carlisle to Squinzano | 1,386.72 mi (2,231.72 km) |
| Carlisle to Statte | 1,352.71 mi (2,176.98 km) |
| Carlisle to Stezzano | 844.24 mi (1,358.67 km) |
| Carlisle to Strada | 1,008.11 mi (1,622.40 km) |
| Carlisle to Stradella | 866.37 mi (1,394.29 km) |
| Carlisle to Striano | 1,259.53 mi (2,027.02 km) |
| Carlisle to Subiaco | 1,153.19 mi (1,855.88 km) |
| Carlisle to Sulmona | 1,170.54 mi (1,883.80 km) |
