| Carlisle to Edgware | 251.58 mi (404.88 km) |
| Carlisle to Edinburgh | 74.02 mi (119.13 km) |
| Carlisle to Edmonton | 255.54 mi (411.25 km) |
| Carlisle to Egg Buckland | 314.09 mi (505.49 km) |
| Carlisle to Elgin | 191.16 mi (307.64 km) |
| Carlisle to Elland | 94.60 mi (152.24 km) |
| Carlisle to Ellesmere Port | 111.39 mi (179.27 km) |
| Carlisle to Ellon | 174.16 mi (280.29 km) |
| Carlisle to Eltham | 268.06 mi (431.40 km) |
| Carlisle to Ely | 216.54 mi (348.50 km) |
| Carlisle to Emsworth | 291.51 mi (469.13 km) |
| Carlisle to Enfield | 253.08 mi (407.29 km) |
| Carlisle to Enfield Lock | 253.13 mi (407.38 km) |
| Carlisle to Englefield Green | 258.52 mi (416.05 km) |
| Carlisle to Enniskillen | 191.54 mi (308.26 km) |
