| Carlisle to Shotley Bridge | 43.11 mi (69.38 km) |
| Carlisle to Shrewsbury | 151.03 mi (243.06 km) |
| Carlisle to Sidcup | 270.56 mi (435.42 km) |
| Carlisle to Sidmouth | 291.21 mi (468.66 km) |
| Carlisle to Sileby | 167.01 mi (268.77 km) |
| Carlisle to Sittingbourne | 288.94 mi (465.00 km) |
| Carlisle to Skegness | 179.91 mi (289.54 km) |
| Carlisle to Skelmersdale | 92.90 mi (149.51 km) |
| Carlisle to Skipton | 74.20 mi (119.42 km) |
| Carlisle to Sleaford | 166.52 mi (267.99 km) |
| Carlisle to Slough | 253.20 mi (407.49 km) |
| Carlisle to Small Heath | 173.59 mi (279.36 km) |
| Carlisle to Smethwick | 170.41 mi (274.25 km) |
| Carlisle to Snaresbrook | 258.94 mi (416.73 km) |
| Carlisle to Snodland | 283.44 mi (456.15 km) |
