| Carlisle to Emeryville (California) | 5,098.21 mi (8,204.78 km) |
| Carlisle to Emmaus (Pennsylvania) | 3,350.51 mi (5,392.12 km) |
| Carlisle to Emporia (Kansas) | 4,224.59 mi (6,798.82 km) |
| Carlisle to Encinitas (California) | 5,227.81 mi (8,413.35 km) |
| Carlisle to Endicott (New York) | 3,299.33 mi (5,309.77 km) |
| Carlisle to Endwell (New York) | 3,296.79 mi (5,305.67 km) |
| Carlisle to Englewood (Colorado) | 4,460.90 mi (7,179.12 km) |
| Carlisle to Englewood (Florida) | 4,302.70 mi (6,924.53 km) |
| Carlisle to Englewood (New Jersey) | 3,275.09 mi (5,270.76 km) |
| Carlisle to Englewood (Ohio) | 3,717.02 mi (5,981.96 km) |
| Carlisle to Enid (Oklahoma) | 4,389.29 mi (7,063.87 km) |
| Carlisle to Ennis (Texas) | 4,562.68 mi (7,342.93 km) |
| Carlisle to Ensley (Florida) | 4,306.19 mi (6,930.14 km) |
| Carlisle to Enterprise (Alabama) | 4,209.13 mi (6,773.95 km) |
| Carlisle to Enterprise (Nevada) | 4,993.37 mi (8,036.06 km) |
