| Carlisle to Enumclaw (Washington) | 4,543.67 mi (7,312.34 km) |
| Carlisle to Ephrata (Pennsylvania) | 3,393.50 mi (5,461.31 km) |
| Carlisle to Erie (Colorado) | 4,441.15 mi (7,147.34 km) |
| Carlisle to Erie (Pennsylvania) | 3,450.17 mi (5,552.52 km) |
| Carlisle to Erlanger (Kentucky) | 3,769.49 mi (6,066.41 km) |
| Carlisle to Escanaba (Michigan) | 3,536.13 mi (5,690.85 km) |
| Carlisle to Escondido (California) | 5,216.92 mi (8,395.83 km) |
| Carlisle to Española (New Mexico) | 4,695.61 mi (7,556.86 km) |
| Carlisle to Essex (Maryland) | 3,445.50 mi (5,544.99 km) |
| Carlisle to Essex Junction (Vermont) | 3,079.08 mi (4,955.30 km) |
| Carlisle to Estelle (Louisiana) | 4,450.68 mi (7,162.68 km) |
| Carlisle to Estero (Florida) | 4,309.72 mi (6,935.82 km) |
| Carlisle to Euclid (Ohio) | 3,529.28 mi (5,679.83 km) |
| Carlisle to Eufaula (Alabama) | 4,151.90 mi (6,681.83 km) |
| Carlisle to Eugene (Oregon) | 4,755.82 mi (7,653.75 km) |
