| Cassano al Ionio to Setubal | 1,349.02 mi (2,171.03 km) |
| Cassano al Ionio to Sever do Vouga | 1,298.87 mi (2,090.33 km) |
| Cassano al Ionio to Silves | 1,346.48 mi (2,166.95 km) |
| Cassano al Ionio to Sines | 1,356.00 mi (2,182.28 km) |
| Cassano al Ionio to Sintra | 1,371.51 mi (2,207.23 km) |
| Cassano al Ionio to Sobrado de Paiva | 1,291.95 mi (2,079.19 km) |
| Cassano al Ionio to Sobral de Monte Agraco | 1,356.22 mi (2,182.63 km) |
| Cassano al Ionio to Soure | 1,317.96 mi (2,121.05 km) |
| Cassano al Ionio to Tabua | 1,283.79 mi (2,066.06 km) |
| Cassano al Ionio to Tavira | 1,305.88 mi (2,101.61 km) |
| Cassano al Ionio to Tomar | 1,310.85 mi (2,109.61 km) |
| Cassano al Ionio to Tondela | 1,285.50 mi (2,068.81 km) |
| Cassano al Ionio to Torre de Moncorvo | 1,232.33 mi (1,983.24 km) |
| Cassano al Ionio to Torres Novas | 1,318.39 mi (2,121.74 km) |
| Cassano al Ionio to Torres Vedras | 1,361.47 mi (2,191.08 km) |
