| Castel Gandolfo to Savona | 275.06 mi (442.67 km) |
| Castel Gandolfo to Scafati | 119.08 mi (191.64 km) |
| Castel Gandolfo to Scalea | 211.90 mi (341.02 km) |
| Castel Gandolfo to Scandiano | 220.10 mi (354.22 km) |
| Castel Gandolfo to Scandicci | 157.30 mi (253.15 km) |
| Castel Gandolfo to Schio | 281.43 mi (452.92 km) |
| Castel Gandolfo to Sciacca | 293.72 mi (472.69 km) |
| Castel Gandolfo to Scicli | 359.50 mi (578.56 km) |
| Castel Gandolfo to Scordia | 328.79 mi (529.14 km) |
| Castel Gandolfo to Scorze | 265.67 mi (427.55 km) |
| Castel Gandolfo to Sedico | 303.17 mi (487.90 km) |
| Castel Gandolfo to Sedriano | 317.14 mi (510.39 km) |
| Castel Gandolfo to Segni | 19.32 mi (31.09 km) |
| Castel Gandolfo to Segrate | 308.28 mi (496.12 km) |
| Castel Gandolfo to Selargius | 251.59 mi (404.90 km) |
