| Castelo Branco to Sacile | 1,094.15 mi (1,760.86 km) |
| Castelo Branco to Sala Consilina | 1,217.90 mi (1,960.01 km) |
| Castelo Branco to Salemi | 1,099.13 mi (1,768.89 km) |
| Castelo Branco to Salerno | 1,172.25 mi (1,886.56 km) |
| Castelo Branco to Salo | 996.09 mi (1,603.06 km) |
| Castelo Branco to Salsomaggiore Terme | 955.10 mi (1,537.08 km) |
| Castelo Branco to Saluzzo | 834.70 mi (1,343.33 km) |
| Castelo Branco to Salzano | 1,068.46 mi (1,719.52 km) |
| Castelo Branco to Samarate | 916.34 mi (1,474.70 km) |
| Castelo Branco to San Benedetto del Tronto | 1,126.24 mi (1,812.51 km) |
| Castelo Branco to San Biagio di Callalta | 1,083.54 mi (1,743.79 km) |
| Castelo Branco to San Bonifacio | 1,027.07 mi (1,652.91 km) |
| Castelo Branco to San Casciano in Val di Pesa | 996.85 mi (1,604.28 km) |
| Castelo Branco to San Cataldo | 1,167.52 mi (1,878.95 km) |
| Castelo Branco to San Cesareo | 1,067.91 mi (1,718.63 km) |
