| Castelo Branco to Spello | 1,065.40 mi (1,714.59 km) |
| Castelo Branco to Spilamberto | 999.94 mi (1,609.25 km) |
| Castelo Branco to Spilimbergo | 1,114.94 mi (1,794.32 km) |
| Castelo Branco to Spinea | 1,069.81 mi (1,721.70 km) |
| Castelo Branco to Spoleto | 1,064.79 mi (1,713.61 km) |
| Castelo Branco to Spoltore | 1,137.55 mi (1,830.70 km) |
| Castelo Branco to Spresiano | 1,079.17 mi (1,736.75 km) |
| Castelo Branco to Squinzano | 1,345.80 mi (2,165.86 km) |
| Castelo Branco to Statte | 1,300.41 mi (2,092.82 km) |
| Castelo Branco to Stezzano | 956.72 mi (1,539.70 km) |
| Castelo Branco to Strada | 1,002.54 mi (1,613.44 km) |
| Castelo Branco to Stradella | 928.32 mi (1,493.98 km) |
| Castelo Branco to Striano | 1,161.50 mi (1,869.26 km) |
| Castelo Branco to Subiaco | 1,083.45 mi (1,743.64 km) |
| Castelo Branco to Sulmona | 1,125.98 mi (1,812.09 km) |
