| Castelo Branco to Sestao | 334.96 mi (539.07 km) |
| Castelo Branco to Sevilla | 195.84 mi (315.18 km) |
| Castelo Branco to Sevilla La Nueva | 187.13 mi (301.16 km) |
| Castelo Branco to Silla | 378.70 mi (609.46 km) |
| Castelo Branco to Silleda | 202.82 mi (326.41 km) |
| Castelo Branco to Sitges | 498.10 mi (801.62 km) |
| Castelo Branco to Socuellamos | 253.25 mi (407.57 km) |
| Castelo Branco to Soller | 541.23 mi (871.03 km) |
| Castelo Branco to Solsona | 494.08 mi (795.14 km) |
| Castelo Branco to Son Servera | 576.97 mi (928.54 km) |
| Castelo Branco to Sonseca | 188.72 mi (303.71 km) |
| Castelo Branco to Sopelana | 339.34 mi (546.12 km) |
| Castelo Branco to Soria | 295.69 mi (475.87 km) |
| Castelo Branco to Suances | 306.84 mi (493.81 km) |
| Castelo Branco to Sueca | 385.45 mi (620.32 km) |
