| Cayenne to Santander | 3,969.21 mi (6,387.83 km) |
| Cayenne to Santany | 4,185.09 mi (6,735.25 km) |
| Cayenne to Santiago de Compostela | 3,741.77 mi (6,021.80 km) |
| Cayenne to Santiago del Teide | 2,832.23 mi (4,558.04 km) |
| Cayenne to Santiponce | 3,676.08 mi (5,916.08 km) |
| Cayenne to Santomera | 3,942.85 mi (6,345.40 km) |
| Cayenne to Santona | 3,983.99 mi (6,411.61 km) |
| Cayenne to Santurce-Antiguo | 3,999.53 mi (6,436.62 km) |
| Cayenne to Sarria | 3,787.28 mi (6,095.04 km) |
| Cayenne to Sauzal | 2,858.54 mi (4,600.37 km) |
| Cayenne to Sedavi | 4,011.75 mi (6,456.29 km) |
| Cayenne to Segorbe | 4,017.88 mi (6,466.15 km) |
| Cayenne to Segovia | 3,875.82 mi (6,237.53 km) |
| Cayenne to Senmanat | 4,190.95 mi (6,744.69 km) |
| Cayenne to Sesena | 3,870.02 mi (6,228.20 km) |
