| Chalons-en-Champagne to Schiltigheim | 155.98 mi (251.02 km) |
| Chalons-en-Champagne to Scionzier | 224.82 mi (361.82 km) |
| Chalons-en-Champagne to Seclin | 125.04 mi (201.23 km) |
| Chalons-en-Champagne to Sedan | 57.59 mi (92.68 km) |
| Chalons-en-Champagne to Selestat | 149.13 mi (240.00 km) |
| Chalons-en-Champagne to Sene | 339.20 mi (545.88 km) |
| Chalons-en-Champagne to Senlis | 82.30 mi (132.45 km) |
| Chalons-en-Champagne to Sens | 71.99 mi (115.85 km) |
| Chalons-en-Champagne to Septemes-les-Vallons | 387.07 mi (622.92 km) |
| Chalons-en-Champagne to Serris | 72.04 mi (115.94 km) |
| Chalons-en-Champagne to Sete | 384.94 mi (619.50 km) |
| Chalons-en-Champagne to Sevran | 83.14 mi (133.79 km) |
| Chalons-en-Champagne to Sevres | 98.25 mi (158.12 km) |
| Chalons-en-Champagne to Seynod | 226.92 mi (365.20 km) |
| Chalons-en-Champagne to Seysses | 404.35 mi (650.75 km) |
