| Chalons-en-Champagne to Settimo Torinese | 308.90 mi (497.13 km) |
| Chalons-en-Champagne to Seveso | 319.93 mi (514.88 km) |
| Chalons-en-Champagne to Sezze | 666.03 mi (1,071.87 km) |
| Chalons-en-Champagne to Siano | 755.75 mi (1,216.27 km) |
| Chalons-en-Champagne to Siena | 512.44 mi (824.70 km) |
| Chalons-en-Champagne to Signa | 480.15 mi (772.72 km) |
| Chalons-en-Champagne to Silea | 435.75 mi (701.27 km) |
| Chalons-en-Champagne to Silvi Paese | 644.81 mi (1,037.72 km) |
| Chalons-en-Champagne to Sinalunga | 530.54 mi (853.83 km) |
| Chalons-en-Champagne to Siniscola | 635.13 mi (1,022.14 km) |
| Chalons-en-Champagne to Sinnai | 708.55 mi (1,140.29 km) |
| Chalons-en-Champagne to Siracusa | 987.33 mi (1,588.95 km) |
| Chalons-en-Champagne to Solaro | 319.64 mi (514.42 km) |
| Chalons-en-Champagne to Soliera | 425.24 mi (684.35 km) |
| Chalons-en-Champagne to Solofra | 759.17 mi (1,221.76 km) |
