| Chalons-en-Champagne to Spilamberto | 438.57 mi (705.82 km) |
| Chalons-en-Champagne to Spilimbergo | 442.52 mi (712.16 km) |
| Chalons-en-Champagne to Spinea | 436.81 mi (702.98 km) |
| Chalons-en-Champagne to Spoleto | 585.73 mi (942.63 km) |
| Chalons-en-Champagne to Spoltore | 650.41 mi (1,046.73 km) |
| Chalons-en-Champagne to Spresiano | 428.91 mi (690.26 km) |
| Chalons-en-Champagne to Squinzano | 891.24 mi (1,434.31 km) |
| Chalons-en-Champagne to Statte | 853.79 mi (1,374.05 km) |
| Chalons-en-Champagne to Stezzano | 336.86 mi (542.13 km) |
| Chalons-en-Champagne to Strada | 497.70 mi (800.96 km) |
| Chalons-en-Champagne to Stradella | 354.37 mi (570.31 km) |
| Chalons-en-Champagne to Striano | 750.85 mi (1,208.38 km) |
| Chalons-en-Champagne to Subiaco | 643.22 mi (1,035.17 km) |
| Chalons-en-Champagne to Sulmona | 664.05 mi (1,068.69 km) |
| Chalons-en-Champagne to Surbo | 895.94 mi (1,441.88 km) |
