| Chicago to Spello | 4,774.01 mi (7,683.03 km) |
| Chicago to Spilamberto | 4,643.43 mi (7,472.87 km) |
| Chicago to Spilimbergo | 4,649.07 mi (7,481.96 km) |
| Chicago to Spinea | 4,647.96 mi (7,480.17 km) |
| Chicago to Spoleto | 4,784.50 mi (7,699.92 km) |
| Chicago to Spoltore | 4,855.19 mi (7,813.68 km) |
| Chicago to Spresiano | 4,639.26 mi (7,466.17 km) |
| Chicago to Squinzano | 5,099.88 mi (8,207.46 km) |
| Chicago to Statte | 5,060.31 mi (8,143.78 km) |
| Chicago to Stezzano | 4,544.05 mi (7,312.94 km) |
| Chicago to Strada | 4,694.99 mi (7,555.85 km) |
| Chicago to Stradella | 4,553.16 mi (7,327.60 km) |
| Chicago to Striano | 4,944.26 mi (7,957.02 km) |
| Chicago to Subiaco | 4,836.54 mi (7,783.67 km) |
| Chicago to Sulmona | 4,864.51 mi (7,828.67 km) |
