| Chicago to Ede | 4,149.36 mi (6,677.75 km) |
| Chicago to Eemnes | 4,127.11 mi (6,641.95 km) |
| Chicago to Eerbeek | 4,161.83 mi (6,697.82 km) |
| Chicago to Eersel | 4,161.37 mi (6,697.07 km) |
| Chicago to Eijsden | 4,196.42 mi (6,753.48 km) |
| Chicago to Eindhoven | 4,164.55 mi (6,702.20 km) |
| Chicago to Elburg | 4,141.86 mi (6,665.67 km) |
| Chicago to Emmeloord | 4,129.12 mi (6,645.17 km) |
| Chicago to Emmen | 4,167.73 mi (6,707.32 km) |
| Chicago to Enkhuizen | 4,113.19 mi (6,619.54 km) |
| Chicago to Enschede | 4,188.13 mi (6,740.15 km) |
| Chicago to Epe | 4,150.22 mi (6,679.14 km) |
| Chicago to Ermelo | 4,138.70 mi (6,660.59 km) |
| Chicago to Etten-Leur | 4,128.43 mi (6,644.06 km) |
| Chicago to Franeker | 4,104.17 mi (6,605.02 km) |
