| Comacchio to Southern Pines (North Carolina) | 4,635.42 mi (7,459.98 km) |
| Comacchio to Southfield (Michigan) | 4,479.53 mi (7,209.10 km) |
| Comacchio to Southgate (Michigan) | 4,489.06 mi (7,224.44 km) |
| Comacchio to Southlake (Texas) | 5,481.11 mi (8,820.99 km) |
| Comacchio to Spanaway (Washington) | 5,520.20 mi (8,883.90 km) |
| Comacchio to Spanish Fork (Utah) | 5,620.08 mi (9,044.64 km) |
| Comacchio to Spanish Lake (Missouri) | 4,921.59 mi (7,920.54 km) |
| Comacchio to Spanish Springs (Nevada) | 5,886.36 mi (9,473.18 km) |
| Comacchio to Sparks (Nevada) | 5,892.55 mi (9,483.15 km) |
| Comacchio to Spartanburg (South Carolina) | 4,755.65 mi (7,653.48 km) |
| Comacchio to Spearfish (South Dakota) | 5,133.36 mi (8,261.35 km) |
| Comacchio to Speedway (Indiana) | 4,717.52 mi (7,592.11 km) |
| Comacchio to Spencer (Iowa) | 4,901.75 mi (7,888.60 km) |
| Comacchio to Spokane (Washington) | 5,361.56 mi (8,628.60 km) |
| Comacchio to Spokane Valley (Washington) | 5,356.64 mi (8,620.67 km) |
