| Cowes to Savignano sul Rubicone | 786.81 mi (1,266.24 km) |
| Cowes to Savona | 636.87 mi (1,024.95 km) |
| Cowes to Scafati | 1,025.62 mi (1,650.58 km) |
| Cowes to Scalea | 1,118.69 mi (1,800.36 km) |
| Cowes to Scandiano | 700.42 mi (1,127.22 km) |
| Cowes to Scandicci | 758.05 mi (1,219.96 km) |
| Cowes to Schio | 677.56 mi (1,090.43 km) |
| Cowes to Sciacca | 1,156.41 mi (1,861.06 km) |
| Cowes to Scicli | 1,246.97 mi (2,006.80 km) |
| Cowes to Scordia | 1,222.76 mi (1,967.84 km) |
| Cowes to Scorze | 712.82 mi (1,147.18 km) |
| Cowes to Sedico | 691.55 mi (1,112.94 km) |
| Cowes to Sedriano | 596.71 mi (960.31 km) |
| Cowes to Segni | 925.32 mi (1,489.15 km) |
| Cowes to Segrate | 608.43 mi (979.17 km) |
