| Cowes to Sestu | 938.45 mi (1,510.28 km) |
| Cowes to Settimo Torinese | 571.25 mi (919.34 km) |
| Cowes to Seveso | 595.74 mi (958.76 km) |
| Cowes to Sezze | 936.43 mi (1,507.03 km) |
| Cowes to Siano | 1,029.11 mi (1,656.19 km) |
| Cowes to Siena | 784.30 mi (1,262.20 km) |
| Cowes to Signa | 753.45 mi (1,212.57 km) |
| Cowes to Silea | 717.03 mi (1,153.95 km) |
| Cowes to Silvi Paese | 922.29 mi (1,484.28 km) |
| Cowes to Sinalunga | 803.53 mi (1,293.16 km) |
| Cowes to Siniscola | 879.56 mi (1,415.52 km) |
| Cowes to Sinnai | 941.16 mi (1,514.64 km) |
| Cowes to Siracusa | 1,249.72 mi (2,011.23 km) |
| Cowes to Solaro | 595.04 mi (957.63 km) |
| Cowes to Soliera | 702.55 mi (1,130.65 km) |
