| Crewe to Savignano sul Rubicone | 917.09 mi (1,475.92 km) |
| Crewe to Savona | 783.65 mi (1,261.17 km) |
| Crewe to Scafati | 1,164.01 mi (1,873.29 km) |
| Crewe to Scalea | 1,256.17 mi (2,021.61 km) |
| Crewe to Scandiano | 835.25 mi (1,344.20 km) |
| Crewe to Scandicci | 895.63 mi (1,441.37 km) |
| Crewe to Schio | 800.93 mi (1,288.97 km) |
| Crewe to Sciacca | 1,309.06 mi (2,106.73 km) |
| Crewe to Scicli | 1,396.68 mi (2,247.73 km) |
| Crewe to Scordia | 1,370.86 mi (2,206.18 km) |
| Crewe to Scorze | 833.72 mi (1,341.75 km) |
| Crewe to Sedico | 807.79 mi (1,300.02 km) |
| Crewe to Sedriano | 733.92 mi (1,181.13 km) |
| Crewe to Segni | 1,065.48 mi (1,714.73 km) |
| Crewe to Segrate | 743.90 mi (1,197.19 km) |
