| Crewe to Sestu | 1,098.36 mi (1,767.64 km) |
| Crewe to Settimo Torinese | 716.89 mi (1,153.72 km) |
| Crewe to Seveso | 730.89 mi (1,176.25 km) |
| Crewe to Sezze | 1,077.17 mi (1,733.53 km) |
| Crewe to Siano | 1,166.69 mi (1,877.61 km) |
| Crewe to Siena | 923.60 mi (1,486.40 km) |
| Crewe to Signa | 891.27 mi (1,434.36 km) |
| Crewe to Silea | 836.36 mi (1,346.00 km) |
| Crewe to Silvi Paese | 1,054.10 mi (1,696.41 km) |
| Crewe to Sinalunga | 941.66 mi (1,515.46 km) |
| Crewe to Siniscola | 1,035.12 mi (1,665.86 km) |
| Crewe to Sinnai | 1,100.78 mi (1,771.54 km) |
| Crewe to Siracusa | 1,397.11 mi (2,248.43 km) |
| Crewe to Solaro | 730.68 mi (1,175.91 km) |
| Crewe to Soliera | 835.30 mi (1,344.29 km) |
