| Crewe to Sangeorgiu de Mures | 1,272.61 mi (2,048.07 km) |
| Crewe to Sangeorz-Bai | 1,253.39 mi (2,017.14 km) |
| Crewe to Sannicolau Mare | 1,134.69 mi (1,826.11 km) |
| Crewe to Santana | 1,159.45 mi (1,865.95 km) |
| Crewe to Satu Mare | 1,166.14 mi (1,876.72 km) |
| Crewe to Scobinti | 1,345.87 mi (2,165.97 km) |
| Crewe to Scornicesti | 1,350.73 mi (2,173.79 km) |
| Crewe to Sebes | 1,257.49 mi (2,023.74 km) |
| Crewe to Seini | 1,183.74 mi (1,905.04 km) |
| Crewe to Sfantu-Gheorghe | 1,351.22 mi (2,174.57 km) |
| Crewe to Sibiu | 1,287.30 mi (2,071.70 km) |
| Crewe to Sighetu Marmatiei | 1,202.97 mi (1,935.99 km) |
| Crewe to Sighisoara | 1,297.73 mi (2,088.50 km) |
| Crewe to Simeria | 1,238.98 mi (1,993.94 km) |
| Crewe to Sinaia | 1,360.73 mi (2,189.88 km) |
