| Darmstadt to Siegburg | 90.56 mi (145.74 km) |
| Darmstadt to Siegen | 75.27 mi (121.14 km) |
| Darmstadt to Sigmaringen | 125.98 mi (202.75 km) |
| Darmstadt to Simbach am Inn | 226.50 mi (364.52 km) |
| Darmstadt to Simmerath | 115.51 mi (185.89 km) |
| Darmstadt to Sindelfingen | 81.61 mi (131.34 km) |
| Darmstadt to Sinsheim | 44.21 mi (71.15 km) |
| Darmstadt to Sinzheim | 79.77 mi (128.38 km) |
| Darmstadt to Sinzig | 77.46 mi (124.66 km) |
| Darmstadt to Soest | 119.77 mi (192.74 km) |
| Darmstadt to Solingen | 112.93 mi (181.74 km) |
| Darmstadt to Soltau | 220.88 mi (355.47 km) |
| Darmstadt to Sommerda | 140.19 mi (225.62 km) |
| Darmstadt to Sondershausen | 141.70 mi (228.04 km) |
| Darmstadt to Sonneberg | 116.17 mi (186.96 km) |
