| Des Moines to Orbetello | 4,985.04 mi (8,022.65 km) |
| Des Moines to Oria | 5,320.68 mi (8,562.81 km) |
| Des Moines to Oristano | 4,993.92 mi (8,036.93 km) |
| Des Moines to Orta Nova | 5,208.49 mi (8,382.26 km) |
| Des Moines to Orte | 5,029.35 mi (8,093.96 km) |
| Des Moines to Ortona | 5,111.13 mi (8,225.57 km) |
| Des Moines to Orvieto | 5,007.07 mi (8,058.09 km) |
| Des Moines to Orzinuovi | 4,805.14 mi (7,733.13 km) |
| Des Moines to Osimo | 5,024.32 mi (8,085.87 km) |
| Des Moines to Ospitaletto | 4,803.64 mi (7,730.71 km) |
| Des Moines to Ostuni | 5,307.55 mi (8,541.68 km) |
| Des Moines to Ottaviano | 5,184.00 mi (8,342.85 km) |
| Des Moines to Ovada | 4,789.16 mi (7,707.41 km) |
| Des Moines to Ozieri | 4,980.50 mi (8,015.34 km) |
| Des Moines to Paceco | 5,241.54 mi (8,435.45 km) |
