| Des Moines to Sacile | 4,875.44 mi (7,846.26 km) |
| Des Moines to Sala Consilina | 5,248.28 mi (8,446.29 km) |
| Des Moines to Salemi | 5,259.37 mi (8,464.14 km) |
| Des Moines to Salerno | 5,202.79 mi (8,373.09 km) |
| Des Moines to Salo | 4,818.92 mi (7,755.30 km) |
| Des Moines to Salsomaggiore Terme | 4,832.44 mi (7,777.06 km) |
| Des Moines to Saluzzo | 4,744.31 mi (7,635.22 km) |
| Des Moines to Salzano | 4,880.71 mi (7,854.75 km) |
| Des Moines to Samarate | 4,752.34 mi (7,648.15 km) |
| Des Moines to San Benedetto del Tronto | 5,063.87 mi (8,149.51 km) |
| Des Moines to San Biagio di Callalta | 4,883.62 mi (7,859.42 km) |
| Des Moines to San Bonifacio | 4,855.72 mi (7,814.52 km) |
| Des Moines to San Casciano in Val di Pesa | 4,929.50 mi (7,933.27 km) |
| Des Moines to San Cataldo | 5,322.59 mi (8,565.88 km) |
| Des Moines to San Cesareo | 5,074.65 mi (8,166.86 km) |
