| Des Moines to Sestu | 5,041.26 mi (8,113.13 km) |
| Des Moines to Settimo Torinese | 4,734.21 mi (7,618.97 km) |
| Des Moines to Seveso | 4,764.58 mi (7,667.86 km) |
| Des Moines to Sezze | 5,099.48 mi (8,206.81 km) |
| Des Moines to Siano | 5,194.57 mi (8,359.85 km) |
| Des Moines to Siena | 4,950.20 mi (7,966.58 km) |
| Des Moines to Signa | 4,920.59 mi (7,918.93 km) |
| Des Moines to Silea | 4,881.93 mi (7,856.70 km) |
| Des Moines to Silvi Paese | 5,091.15 mi (8,193.41 km) |
| Des Moines to Sinalunga | 4,970.14 mi (7,998.66 km) |
| Des Moines to Siniscola | 5,008.80 mi (8,060.89 km) |
| Des Moines to Sinnai | 5,045.66 mi (8,120.20 km) |
| Des Moines to Siracusa | 5,394.39 mi (8,681.43 km) |
| Des Moines to Solaro | 4,763.79 mi (7,666.57 km) |
| Des Moines to Soliera | 4,871.55 mi (7,840.00 km) |
