| Des Moines to Smolyan | 5,521.90 mi (8,886.64 km) |
| Des Moines to Sofia | 5,417.60 mi (8,718.78 km) |
| Des Moines to Sopot | 5,468.88 mi (8,801.31 km) |
| Des Moines to Sozopol | 5,579.98 mi (8,980.11 km) |
| Des Moines to Sredets | 5,566.91 mi (8,959.08 km) |
| Des Moines to Stamboliyski | 5,487.94 mi (8,831.99 km) |
| Des Moines to Stara Zagora | 5,510.59 mi (8,868.43 km) |
| Des Moines to Svilengrad | 5,563.79 mi (8,954.05 km) |
| Des Moines to Svishtov | 5,439.46 mi (8,753.97 km) |
| Des Moines to Targovishte | 5,499.43 mi (8,850.48 km) |
| Des Moines to Teteven | 5,438.76 mi (8,752.84 km) |
| Des Moines to Troyan | 5,455.79 mi (8,780.24 km) |
| Des Moines to Tryavna | 5,483.13 mi (8,824.24 km) |
| Des Moines to Tutrakan | 5,458.91 mi (8,785.26 km) |
| Des Moines to Varna | 5,544.96 mi (8,923.75 km) |
