| Desborough to Sestu | 1,023.27 mi (1,646.80 km) |
| Desborough to Settimo Torinese | 637.47 mi (1,025.92 km) |
| Desborough to Seveso | 649.85 mi (1,045.83 km) |
| Desborough to Sezze | 996.45 mi (1,603.64 km) |
| Desborough to Siano | 1,085.57 mi (1,747.06 km) |
| Desborough to Siena | 842.82 mi (1,356.40 km) |
| Desborough to Signa | 810.34 mi (1,304.12 km) |
| Desborough to Silea | 754.68 mi (1,214.54 km) |
| Desborough to Silvi Paese | 972.59 mi (1,565.24 km) |
| Desborough to Sinalunga | 860.73 mi (1,385.21 km) |
| Desborough to Siniscola | 958.03 mi (1,541.81 km) |
| Desborough to Sinnai | 1,025.52 mi (1,650.42 km) |
| Desborough to Siracusa | 1,317.33 mi (2,120.03 km) |
| Desborough to Solaro | 649.69 mi (1,045.57 km) |
| Desborough to Soliera | 753.96 mi (1,213.38 km) |
