| Despotovac to Smolyan | 239.20 mi (384.95 km) |
| Despotovac to Sofia | 134.91 mi (217.12 km) |
| Despotovac to Sopot | 193.78 mi (311.86 km) |
| Despotovac to Sozopol | 335.63 mi (540.15 km) |
| Despotovac to Sredets | 314.01 mi (505.35 km) |
| Despotovac to Stamboliyski | 206.38 mi (332.14 km) |
| Despotovac to Stara Zagora | 240.82 mi (387.57 km) |
| Despotovac to Svilengrad | 289.37 mi (465.70 km) |
| Despotovac to Svishtov | 197.78 mi (318.30 km) |
| Despotovac to Targovishte | 263.71 mi (424.40 km) |
| Despotovac to Teteven | 163.27 mi (262.76 km) |
| Despotovac to Troyan | 184.29 mi (296.58 km) |
| Despotovac to Tryavna | 220.51 mi (354.88 km) |
| Despotovac to Tutrakan | 257.30 mi (414.09 km) |
| Despotovac to Varna | 329.52 mi (530.31 km) |
