| Destin to Sestu | 5,194.50 mi (8,359.74 km) |
| Destin to Settimo Torinese | 4,955.45 mi (7,975.02 km) |
| Destin to Seveso | 5,000.41 mi (8,047.39 km) |
| Destin to Sezze | 5,306.88 mi (8,540.59 km) |
| Destin to Siano | 5,404.31 mi (8,697.39 km) |
| Destin to Siena | 5,169.25 mi (8,319.11 km) |
| Destin to Signa | 5,144.11 mi (8,278.65 km) |
| Destin to Silea | 5,136.35 mi (8,266.16 km) |
| Destin to Silvi Paese | 5,318.36 mi (8,559.07 km) |
| Destin to Sinalunga | 5,190.41 mi (8,353.16 km) |
| Destin to Siniscola | 5,182.42 mi (8,340.29 km) |
| Destin to Sinnai | 5,199.68 mi (8,368.08 km) |
| Destin to Siracusa | 5,563.26 mi (8,953.20 km) |
| Destin to Solaro | 4,998.94 mi (8,045.01 km) |
| Destin to Soliera | 5,106.17 mi (8,217.59 km) |
