| Destin to Anoka (Minnesota) | 1,090.03 mi (1,754.23 km) |
| Destin to Ansonia (Connecticut) | 1,063.03 mi (1,710.78 km) |
| Destin to Antelope (California) | 2,053.17 mi (3,304.26 km) |
| Destin to Anthem (Arizona) | 1,515.59 mi (2,439.10 km) |
| Destin to Antioch (California) | 2,072.47 mi (3,335.32 km) |
| Destin to Antioch (Illinois) | 839.28 mi (1,350.70 km) |
| Destin to Apache Junction (Arizona) | 1,481.24 mi (2,383.83 km) |
| Destin to Apex (North Carolina) | 573.26 mi (922.57 km) |
| Destin to Apollo Beach (Florida) | 305.73 mi (492.02 km) |
| Destin to Apopka (Florida) | 319.03 mi (513.43 km) |
| Destin to Apple Valley (California) | 1,807.64 mi (2,909.11 km) |
| Destin to Apple Valley (Minnesota) | 1,056.86 mi (1,700.86 km) |
| Destin to Appleton (Wisconsin) | 964.92 mi (1,552.89 km) |
| Destin to Arbutus (Maryland) | 824.37 mi (1,326.70 km) |
| Destin to Arcadia (California) | 1,854.87 mi (2,985.13 km) |
