| Destin to Darby (Pennsylvania) | 911.81 mi (1,467.42 km) |
| Destin to Dardenne Prairie (Missouri) | 626.33 mi (1,007.98 km) |
| Destin to Darien (Illinois) | 788.69 mi (1,269.27 km) |
| Destin to Davenport (Iowa) | 804.82 mi (1,295.24 km) |
| Destin to Davidson (North Carolina) | 480.22 mi (772.84 km) |
| Destin to Davie (Florida) | 480.03 mi (772.54 km) |
| Destin to Davis (California) | 2,072.37 mi (3,335.15 km) |
| Destin to Dayton (Nevada) | 1,961.79 mi (3,157.19 km) |
| Destin to Dayton (Ohio) | 660.98 mi (1,063.75 km) |
| Destin to Daytona Beach (Florida) | 332.47 mi (535.07 km) |
| Destin to De Pere (Wisconsin) | 973.73 mi (1,567.07 km) |
| Destin to De Witt (New York) | 1,043.68 mi (1,679.64 km) |
| Destin to Dearborn (Michigan) | 842.96 mi (1,356.61 km) |
| Destin to Dearborn Heights (Michigan) | 842.46 mi (1,355.80 km) |
| Destin to DeBary (Florida) | 326.21 mi (524.99 km) |
