| Destin to Dixon (Illinois) | 808.52 mi (1,301.19 km) |
| Destin to Dobbs Ferry (New York) | 1,016.68 mi (1,636.20 km) |
| Destin to Doctor Phillips (Florida) | 328.41 mi (528.53 km) |
| Destin to Dodge City (Kansas) | 925.92 mi (1,490.12 km) |
| Destin to Dolton (Illinois) | 778.69 mi (1,253.18 km) |
| Destin to Donna (Texas) | 763.15 mi (1,228.17 km) |
| Destin to Dorado (Puerto Rico) | 1,510.41 mi (2,430.76 km) |
| Destin to Doral (Florida) | 488.67 mi (786.43 km) |
| Destin to Doraville (Georgia) | 274.64 mi (441.99 km) |
| Destin to Dothan (Alabama) | 85.65 mi (137.85 km) |
| Destin to Douglas (Arizona) | 1,367.15 mi (2,200.22 km) |
| Destin to Douglas (Georgia) | 227.58 mi (366.26 km) |
| Destin to Douglasville (Georgia) | 253.05 mi (407.24 km) |
| Destin to Dover (Delaware) | 866.47 mi (1,394.45 km) |
| Destin to Dover (New Hampshire) | 1,230.90 mi (1,980.94 km) |
