| Destin to Dumas (Texas) | 971.36 mi (1,563.25 km) |
| Destin to Dumont (New Jersey) | 1,008.82 mi (1,623.53 km) |
| Destin to Duncan (Oklahoma) | 725.81 mi (1,168.08 km) |
| Destin to Duncanville (Texas) | 634.11 mi (1,020.50 km) |
| Destin to Dundalk (Maryland) | 833.25 mi (1,340.99 km) |
| Destin to Dunedin (Florida) | 275.63 mi (443.58 km) |
| Destin to Dunkirk (New York) | 923.59 mi (1,486.38 km) |
| Destin to Dunmore (Pennsylvania) | 972.64 mi (1,565.32 km) |
| Destin to Dunwoody (Georgia) | 275.63 mi (443.58 km) |
| Destin to Durango (Colorado) | 1,313.53 mi (2,113.92 km) |
| Destin to Durant (Oklahoma) | 630.84 mi (1,015.23 km) |
| Destin to Durham (North Carolina) | 583.04 mi (938.30 km) |
| Destin to Dyer (Indiana) | 769.30 mi (1,238.07 km) |
| Destin to Dyersburg (Tennessee) | 425.05 mi (684.05 km) |
| Destin to Eagan (Minnesota) | 1,060.73 mi (1,707.08 km) |
