| Destin to Euless (Texas) | 646.54 mi (1,040.50 km) |
| Destin to Eureka (California) | 2,216.30 mi (3,566.78 km) |
| Destin to Eureka (Missouri) | 608.35 mi (979.05 km) |
| Destin to Eustis (Florida) | 306.84 mi (493.81 km) |
| Destin to Evans (Colorado) | 1,234.51 mi (1,986.75 km) |
| Destin to Evans (Georgia) | 335.24 mi (539.51 km) |
| Destin to Evanston (Illinois) | 807.89 mi (1,300.18 km) |
| Destin to Evanston (Wyoming) | 1,556.27 mi (2,504.58 km) |
| Destin to Evansville (Indiana) | 528.13 mi (849.95 km) |
| Destin to Everett (Massachusetts) | 1,189.55 mi (1,914.40 km) |
| Destin to Everett (Washington) | 2,234.58 mi (3,596.20 km) |
| Destin to Evergreen Park (Illinois) | 785.56 mi (1,264.24 km) |
| Destin to Ewa Beach (Hawaii) | 4,421.80 mi (7,116.20 km) |
| Destin to Ewa Gentry (Hawaii) | 4,422.44 mi (7,117.23 km) |
| Destin to Excelsior Springs (Missouri) | 758.18 mi (1,220.17 km) |
