| Destin to Firestone (Colorado) | 1,237.59 mi (1,991.71 km) |
| Destin to Fish Hawk (Florida) | 311.10 mi (500.67 km) |
| Destin to Fishers (Indiana) | 661.40 mi (1,064.43 km) |
| Destin to Fitchburg (Massachusetts) | 1,168.24 mi (1,880.10 km) |
| Destin to Fitchburg (Wisconsin) | 885.06 mi (1,424.36 km) |
| Destin to Five Corners (Washington) | 2,204.84 mi (3,548.35 km) |
| Destin to Five Forks (South Carolina) | 392.23 mi (631.23 km) |
| Destin to Flagstaff (Arizona) | 1,493.48 mi (2,403.52 km) |
| Destin to Flat Rock (Michigan) | 827.91 mi (1,332.39 km) |
| Destin to Fleming Island (Florida) | 284.69 mi (458.16 km) |
| Destin to Flint (Michigan) | 885.87 mi (1,425.67 km) |
| Destin to Floral Park (New York) | 1,009.91 mi (1,625.29 km) |
| Destin to Florence (Alabama) | 314.24 mi (505.72 km) |
| Destin to Florence (Arizona) | 1,474.32 mi (2,372.69 km) |
| Destin to Florence (Kentucky) | 602.77 mi (970.07 km) |
