| Destin to Fortuna Foothills (Arizona) | 1,647.45 mi (2,651.32 km) |
| Destin to Foster City (California) | 2,096.35 mi (3,373.76 km) |
| Destin to Fostoria (Ohio) | 763.14 mi (1,228.15 km) |
| Destin to Fountain (Colorado) | 1,181.23 mi (1,901.01 km) |
| Destin to Fountain Hills (Arizona) | 1,493.39 mi (2,403.38 km) |
| Destin to Fountain Inn (South Carolina) | 387.55 mi (623.70 km) |
| Destin to Fountain Valley (California) | 1,850.57 mi (2,978.20 km) |
| Destin to Fountainebleau (Florida) | 491.13 mi (790.40 km) |
| Destin to Four Corners (Oregon) | 2,209.86 mi (3,556.42 km) |
| Destin to Four Corners (Texas) | 551.81 mi (888.05 km) |
| Destin to Four Square Mile (Colorado) | 1,219.94 mi (1,963.31 km) |
| Destin to Fox Crossing (Wisconsin) | 961.66 mi (1,547.65 km) |
| Destin to Fox Lake (Illinois) | 836.51 mi (1,346.24 km) |
| Destin to Framingham (Massachusetts) | 1,170.19 mi (1,883.24 km) |
| Destin to Franconia (Virginia) | 783.49 mi (1,260.90 km) |
