| Destin to Frederick (Maryland) | 807.31 mi (1,299.24 km) |
| Destin to Fredericksburg (Texas) | 739.47 mi (1,190.06 km) |
| Destin to Fredericksburg (Virginia) | 748.11 mi (1,203.97 km) |
| Destin to Frederickson (Washington) | 2,223.68 mi (3,578.66 km) |
| Destin to Freeport (Illinois) | 840.29 mi (1,352.31 km) |
| Destin to Freeport (New York) | 1,011.39 mi (1,627.67 km) |
| Destin to Freeport (Texas) | 542.87 mi (873.66 km) |
| Destin to Fremont (California) | 2,080.85 mi (3,348.80 km) |
| Destin to Fremont (Nebraska) | 945.37 mi (1,521.43 km) |
| Destin to Fremont (Ohio) | 779.94 mi (1,255.19 km) |
| Destin to French Valley (California) | 1,802.22 mi (2,900.39 km) |
| Destin to Fresno (California) | 1,957.62 mi (3,150.48 km) |
| Destin to Fresno (Texas) | 541.80 mi (871.95 km) |
| Destin to Fridley (Minnesota) | 1,079.58 mi (1,737.42 km) |
| Destin to Friendly (Maryland) | 790.58 mi (1,272.31 km) |
