| Detroit to Orlando (Florida) | 965.88 mi (1,554.44 km) |
| Detroit to Tampa (Florida) | 994.86 mi (1,601.07 km) |
| Detroit to Dallas (Texas) | 997.05 mi (1,604.59 km) |
| Detroit to Houston (Texas) | 1,105.74 mi (1,779.52 km) |
| Detroit to Denver (Colorado) | 1,145.25 mi (1,843.10 km) |
| Detroit to Miami (Florida) | 1,158.59 mi (1,864.57 km) |
| Detroit to Phoenix (Arizona) | 1,681.85 mi (2,706.67 km) |
| Detroit to Las Vegas (Nevada) | 1,759.81 mi (2,832.14 km) |
| Detroit to Seattle (Washington) | 1,928.64 mi (3,103.85 km) |
| Detroit to Riverside (California) | 1,937.27 mi (3,117.74 km) |
| Detroit to Portland (Oregon) | 1,958.87 mi (3,152.50 km) |
| Detroit to San Diego (California) | 1,960.12 mi (3,154.51 km) |
| Detroit to Los Angeles (California) | 1,983.06 mi (3,191.43 km) |
| Detroit to San Francisco (California) | 2,085.72 mi (3,356.64 km) |
| Detroit to Chicago (Illinois) | 237.95 mi (382.94 km) |
| Detroit to Washington (District of Columbia) | 399.29 mi (642.60 km) |
| Detroit to Baltimore (Maryland) | 400.12 mi (643.93 km) |
| Detroit to Philadelphia (Pennsylvania) | 445.39 mi (716.79 km) |
| Detroit to St. Louis (Missouri) | 455.62 mi (733.26 km) |
| Detroit to Brooklyn (New York) | 488.15 mi (785.60 km) |
| Detroit to New York (New York) | 488.50 mi (786.16 km) |
| Detroit to Queens (New York) | 493.79 mi (794.68 km) |
| Detroit to Minneapolis (Minnesota) | 537.93 mi (865.71 km) |
| Detroit to Atlanta (Georgia) | 599.91 mi (965.46 km) |
| Detroit to Boston (Massachusetts) | 613.13 mi (986.73 km) |
