| Detroit to Sceaux | 3,931.30 mi (6,326.82 km) |
| Detroit to Schiltigheim | 4,152.74 mi (6,683.19 km) |
| Detroit to Scionzier | 4,198.08 mi (6,756.16 km) |
| Detroit to Seclin | 3,902.67 mi (6,280.75 km) |
| Detroit to Sedan | 4,004.99 mi (6,445.41 km) |
| Detroit to Selestat | 4,153.80 mi (6,684.89 km) |
| Detroit to Sene | 3,762.82 mi (6,055.68 km) |
| Detroit to Senlis | 3,929.00 mi (6,323.11 km) |
| Detroit to Sens | 3,990.69 mi (6,422.39 km) |
| Detroit to Septemes-les-Vallons | 4,247.75 mi (6,836.09 km) |
| Detroit to Serris | 3,948.52 mi (6,354.53 km) |
| Detroit to Sete | 4,176.79 mi (6,721.90 km) |
| Detroit to Sevran | 3,935.90 mi (6,334.21 km) |
| Detroit to Sevres | 3,926.66 mi (6,319.34 km) |
| Detroit to Seynod | 4,185.79 mi (6,736.38 km) |
