| Detroit to Senftenberg | 4,278.26 mi (6,885.19 km) |
| Detroit to Siegburg | 4,054.05 mi (6,524.36 km) |
| Detroit to Siegen | 4,081.77 mi (6,568.97 km) |
| Detroit to Sigmaringen | 4,228.92 mi (6,805.78 km) |
| Detroit to Simbach am Inn | 4,367.81 mi (7,029.31 km) |
| Detroit to Simmerath | 4,026.69 mi (6,480.33 km) |
| Detroit to Sindelfingen | 4,197.43 mi (6,755.12 km) |
| Detroit to Sinsheim | 4,173.16 mi (6,716.05 km) |
| Detroit to Sinzheim | 4,163.34 mi (6,700.25 km) |
| Detroit to Sinzig | 4,064.76 mi (6,541.59 km) |
| Detroit to Soest | 4,061.15 mi (6,535.78 km) |
| Detroit to Solingen | 4,036.86 mi (6,496.70 km) |
| Detroit to Soltau | 4,074.57 mi (6,557.39 km) |
| Detroit to Sommerda | 4,186.71 mi (6,737.86 km) |
| Detroit to Sondershausen | 4,170.02 mi (6,711.00 km) |
