| Detroit to Solymar | 4,615.73 mi (7,428.30 km) |
| Detroit to Sopron | 4,525.16 mi (7,282.54 km) |
| Detroit to Szarvas | 4,706.37 mi (7,574.16 km) |
| Detroit to Szazhalombatta | 4,627.59 mi (7,447.39 km) |
| Detroit to Szeged | 4,718.26 mi (7,593.30 km) |
| Detroit to Szeghalom | 4,721.75 mi (7,598.92 km) |
| Detroit to Szekesfehervar | 4,613.45 mi (7,424.63 km) |
| Detroit to Szekszard | 4,660.33 mi (7,500.07 km) |
| Detroit to Szentendre | 4,615.99 mi (7,428.72 km) |
| Detroit to Szentes | 4,705.10 mi (7,572.13 km) |
| Detroit to Szentgotthard | 4,544.31 mi (7,313.36 km) |
| Detroit to Szigethalom | 4,630.41 mi (7,451.93 km) |
| Detroit to Szigetszentmiklos | 4,630.61 mi (7,452.24 km) |
| Detroit to Szigetvar | 4,639.58 mi (7,466.69 km) |
| Detroit to Szolnok | 4,680.01 mi (7,531.75 km) |
