| Detroit to Savignano sul Rubicone | 4,510.36 mi (7,258.73 km) |
| Detroit to Savona | 4,342.81 mi (6,989.07 km) |
| Detroit to Scafati | 4,735.97 mi (7,621.80 km) |
| Detroit to Scalea | 4,828.85 mi (7,771.29 km) |
| Detroit to Scandiano | 4,421.49 mi (7,115.71 km) |
| Detroit to Scandicci | 4,475.18 mi (7,202.11 km) |
| Detroit to Schio | 4,404.03 mi (7,087.60 km) |
| Detroit to Sciacca | 4,814.47 mi (7,748.14 km) |
| Detroit to Scicli | 4,914.76 mi (7,909.55 km) |
| Detroit to Scordia | 4,898.80 mi (7,883.85 km) |
| Detroit to Scorze | 4,439.35 mi (7,144.44 km) |
| Detroit to Sedico | 4,417.33 mi (7,109.01 km) |
| Detroit to Sedriano | 4,317.40 mi (6,948.18 km) |
| Detroit to Segni | 4,634.66 mi (7,458.76 km) |
| Detroit to Segrate | 4,330.37 mi (6,969.06 km) |
