| Didymoteicho to Santeramo in Colle | 508.12 mi (817.74 km) |
| Didymoteicho to Santo Stefano di Magra | 861.91 mi (1,387.11 km) |
| Didymoteicho to Santo Stino di Livenza | 754.06 mi (1,213.54 km) |
| Didymoteicho to Sarezzo | 867.38 mi (1,395.91 km) |
| Didymoteicho to Sarno | 619.48 mi (996.96 km) |
| Didymoteicho to Saronno | 921.66 mi (1,483.26 km) |
| Didymoteicho to Sarzana | 859.28 mi (1,382.88 km) |
| Didymoteicho to Sassari | 934.31 mi (1,503.62 km) |
| Didymoteicho to Sasso Marconi | 799.08 mi (1,285.99 km) |
| Didymoteicho to Sassuolo | 823.45 mi (1,325.21 km) |
| Didymoteicho to Sava | 471.08 mi (758.14 km) |
| Didymoteicho to Saviano | 623.83 mi (1,003.96 km) |
| Didymoteicho to Savigliano | 977.83 mi (1,573.66 km) |
| Didymoteicho to Savignano sul Panaro | 810.60 mi (1,304.54 km) |
| Didymoteicho to Savignano sul Rubicone | 739.61 mi (1,190.29 km) |
