| Didymoteicho to Savona | 933.59 mi (1,502.48 km) |
| Didymoteicho to Scafati | 624.79 mi (1,005.51 km) |
| Didymoteicho to Scalea | 570.98 mi (918.91 km) |
| Didymoteicho to Scandiano | 828.68 mi (1,333.63 km) |
| Didymoteicho to Scandicci | 795.56 mi (1,280.33 km) |
| Didymoteicho to Schio | 814.67 mi (1,311.09 km) |
| Didymoteicho to Sciacca | 762.34 mi (1,226.86 km) |
| Didymoteicho to Scicli | 706.04 mi (1,136.27 km) |
| Didymoteicho to Scordia | 681.91 mi (1,097.42 km) |
| Didymoteicho to Scorze | 777.05 mi (1,250.55 km) |
| Didymoteicho to Sedico | 789.23 mi (1,270.14 km) |
| Didymoteicho to Sedriano | 922.92 mi (1,485.29 km) |
| Didymoteicho to Segni | 697.22 mi (1,122.07 km) |
| Didymoteicho to Segrate | 907.45 mi (1,460.39 km) |
| Didymoteicho to Selargius | 923.48 mi (1,486.20 km) |
