| Didymoteicho to Somma Lombardo | 938.41 mi (1,510.23 km) |
| Didymoteicho to Somma Vesuviana | 628.33 mi (1,011.20 km) |
| Didymoteicho to Sommacampagna | 832.65 mi (1,340.02 km) |
| Didymoteicho to Sona | 833.99 mi (1,342.18 km) |
| Didymoteicho to Sondrio | 892.05 mi (1,435.61 km) |
| Didymoteicho to Sora | 666.20 mi (1,072.14 km) |
| Didymoteicho to Sorbolo | 843.44 mi (1,357.39 km) |
| Didymoteicho to Soresina | 877.83 mi (1,412.74 km) |
| Didymoteicho to Sorisole | 894.30 mi (1,439.23 km) |
| Didymoteicho to Sorrento | 633.89 mi (1,020.14 km) |
| Didymoteicho to Sorso | 932.66 mi (1,500.96 km) |
| Didymoteicho to Sortino | 677.40 mi (1,090.16 km) |
| Didymoteicho to Soverato Marina | 557.42 mi (897.08 km) |
| Didymoteicho to Sovicille | 790.17 mi (1,271.66 km) |
| Didymoteicho to Spello | 716.26 mi (1,152.71 km) |
