| Didymoteicho to Spilamberto | 812.02 mi (1,306.82 km) |
| Didymoteicho to Spilimbergo | 754.24 mi (1,213.83 km) |
| Didymoteicho to Spinea | 773.09 mi (1,244.16 km) |
| Didymoteicho to Spoleto | 714.54 mi (1,149.93 km) |
| Didymoteicho to Spoltore | 639.61 mi (1,029.35 km) |
| Didymoteicho to Spresiano | 774.97 mi (1,247.19 km) |
| Didymoteicho to Squinzano | 445.69 mi (717.27 km) |
| Didymoteicho to Statte | 488.03 mi (785.40 km) |
| Didymoteicho to Stezzano | 893.06 mi (1,437.24 km) |
| Didymoteicho to Strada | 787.91 mi (1,268.02 km) |
| Didymoteicho to Stradella | 901.67 mi (1,451.09 km) |
| Didymoteicho to Striano | 622.08 mi (1,001.14 km) |
| Didymoteicho to Subiaco | 692.37 mi (1,114.26 km) |
| Didymoteicho to Sulmona | 649.86 mi (1,045.86 km) |
| Didymoteicho to Surbo | 441.83 mi (711.06 km) |
