| Difficult Run to Dendermonde | 3,860.35 mi (6,212.63 km) |
| Difficult Run to Dessel | 3,896.11 mi (6,270.18 km) |
| Difficult Run to Destelbergen | 3,847.80 mi (6,192.44 km) |
| Difficult Run to Deurne | 3,870.07 mi (6,228.28 km) |
| Difficult Run to Diepenbeek | 3,916.75 mi (6,303.39 km) |
| Difficult Run to Diest | 3,899.97 mi (6,276.40 km) |
| Difficult Run to Diksmuide | 3,810.40 mi (6,132.24 km) |
| Difficult Run to Dilbeek | 3,871.53 mi (6,230.63 km) |
| Difficult Run to Dinant | 3,913.43 mi (6,298.05 km) |
| Difficult Run to Dison | 3,941.94 mi (6,343.93 km) |
| Difficult Run to Dour | 3,863.62 mi (6,217.89 km) |
| Difficult Run to Drongen | 3,842.41 mi (6,183.76 km) |
| Difficult Run to Duffel | 3,875.45 mi (6,236.93 km) |
| Difficult Run to Durbuy | 3,933.11 mi (6,329.72 km) |
| Difficult Run to Ecaussinnes-Lalaing | 3,875.69 mi (6,237.32 km) |
